Matchup · Original Sinister Six

Spider-Man vs. Mysterio

Quentin Beck, one of the original Sinister Six. In this site's ratings, the classic Peter Parker Spider-Man wins 75% of their one-on-one fights, so Spider-Man is the favorite.

Spider-Man (Peter Parker)75%Favored

Mysterio25%Underdog

The verdict: Spider-Man wins most nights

Fight rules: both fighters at their peak, no preparation, no allies, only their own powers and personal gear. A win is a knockout, a restraint they can't escape, or a forced surrender. The percentages are fan estimates, not official information.

Spider-Man's edge

Spider-sense ignores illusions that can't hurt him, and Beck is a poor brawler.

Mysterio's edge

Stage illusions, hallucinogenic gas, holograms, robots and special-effects traps built by a Hollywood effects master.

Odds for every Spider-Man

Each version of Spider-Man's chance of beating Mysterio. The best placed, Cosmic Spider-Man, wins 94% of the time; the worst placed, Spider-Ham, wins 69%. The last column says what moves each version away from classic Peter's 75%.

Spider-Man	Spidey wins	Outcome	What changes
Peter Parker Earth-616 comics	75%	Favored	The baseline Spider-Man
Miles Morales Earth-616 comics	75%	Favored	Overall −3 for this version; +3: Venom strike: one clean jolt can stun or paralyze a living opponent.
Ben Reilly Earth-616 comics	76%	Favored	Overall −2 for this version; +3: Stingers: a sedative dart can end it against an opponent without superhuman toughness.
Superior Spider-Man Earth-616 comics	79%	Favored	Overall +2 for this version; +4: Otto reverse-engineers tech-based opponents faster than anyone alive.
Black-suit Peter Earth-616 comics	79%	Favored	Overall +5 for this version
Iron Spider Peter Earth-616 comics	77%	Favored	Overall +3 for this version
Cosmic Spider-Man Earth-616 comics	94%	Favored	Overall +40 for this version
Spider-Woman Earth-616 comics	76%	Favored	Overall −3 for this version; +4: Venom blasts stun or knock out living opponents.
Silk Earth-616 comics	74%	Favored	Overall −1 for this version
Ultimate Peter Alternate comics	73%	Favored	Overall −3 for this version
Ultimate Peter (2024) Alternate comics	72%	Favored	Overall −4 for this version
Spider-Gwen Alternate comics	73%	Favored	Overall −3 for this version
Spider-Man 2099 Alternate comics	77%	Favored	+3: Talons and a paralytic bite can end it against anything short of superhuman toughness.
Spider-Man Noir Alternate comics	76%	Favored	Overall −2 for this version; +3: He carries pistols, and a bullet ends it against an opponent without superhuman toughness.
Spider-Ham Alternate comics	69%	Favored	Overall −8 for this version
Spider-Punk Alternate comics	76%	Favored	Overall −1 for this version; +2: Sonic blasts stagger living opponents.
Maguire's Peter Film	70%	Favored	Overall −4 for this version; −2: Emotional pressure once took his powers away, so a mind-game specialist has an opening.
Garfield's Peter Film	72%	Favored	Overall −4 for this version
Holland's Peter Film	76%	Favored	Overall −2 for this version; +4: He beat Mysterio's illusions by trusting his spider-sense over his eyes.
Spider-Verse Miles Film	73%	Favored	Overall −5 for this version; +3: Venom strike can stun a living opponent.
Spider-Verse Gwen Film	71%	Favored	Overall −5 for this version
Peter B. Parker Film	73%	Favored	Overall −5 for this version; +2: Twenty-two years against these villains.
1994 animated Peter TV and animation	74%	Favored	Overall −3 for this version; +2: He has fought nearly every one of these villains.
Spectacular Peter TV and animation	71%	Favored	Overall −5 for this version
Insomniac Peter Video games	78%	Favored	Overall +1 for this version; +3: An engineer with an arsenal built to short out and dismantle tech.
Insomniac Miles Video games	81%	Favored	Overall +1 for this version; +4: His venom blasts hit far harder than the comic version's.; +4: Bio-electric venom fries electronics, shields and drones.

Tale of the tape

Eight stats on a 1-to-10 scale, classic Spider-Man against Mysterio. How the stat scales work.

StatSpider-ManMysterio

Strength63

Speed64

Agility105

Durability64

Size44

Fighting skill75

Intelligence77

Ranged attack35

Mysterio's power set

Illusions9/10
Holograms, gas and stagecraft.
Special effects9/10
Hollywood-level tricks.
Fishbowl helmet7/10
Sensors and protection.
Hypnosis6/10
Hypnotic tricks.

Who is Mysterio?

Quentin Beck was a Hollywood special-effects artist and stuntman who craved fame and turned to crime as Mysterio, a master of illusions. He debuted in Amazing Spider-Man #13 (1964) and was a founding member of the Sinister Six. He uses hallucinogenic gas, holograms and robots. He has died and returned several times.

First appearance: Amazing Spider-Man #13 (1964)

Affiliations

Sinister Six: Founding member.
Hollywood: Special-effects artist.
Kindred: Worked with Kindred against Peter.